Post Graduate Department of Chemistry is one of the vibrant departments in St. Joseph's College for Women, Alappuzha situated in Block B of the College. Department of Chemistry was established in 1954. Mrs. Saraswathy Nair and Sr. Genevieve D'silva were the teaching faculty. B.Sc. Chemistry was started in 1957. The first batch of B.Sc. Chemistry students came out successfully in 1960.

The department has state-of-the-art infrastructural facilities in terms of well-equipped laboratories with modern instruments and well-furnished and spacious classrooms. The Department caters to one core, four complementary undergraduate students and postgraduate students. 

The year 1998-99 saw the inception of UGC-sponsored job-oriented degree course for clinical nutrition and dietetics, with chemistry as one of the main subjects.The Department of Chemistry at our college has witnessed remarkable growth and academic advancement in recent years. In the academic year 2020–21, the department was elevated to the status of a Post Graduate Department, offering advanced studies and fostering academic excellence. Building on this progress, in 2022, the department achieved another milestone by becoming a recognized Research Center under University of Kerala, encouraging scholarly research and innovation in the field of chemical sciences. Further aligning with the National Education Policy (NEP) 2020, the department successfully implemented the Four-Year Undergraduate Programme in 2024, aimed at providing a holistic and multidisciplinary education to students. The Department of Chemistry continues to be a vibrant hub for learning, research, and academic development.

"We strive to reach out to perfection through an earnest academic pursuit for 'Knowledge' and our efforts blossom into 'Virtue' through our creative and empathetic involvement in the society to transform it"

At present, the department is well-equipped with young and talented teachers who strive to bring perfection in everything. The department was sponsored by DST-FIST.  The well-equipped research lab allowed us to mobilize resources for the research. 

The Department offers various certificate courses to enrich the curriculum namely 'Instrumentation and Analytical Techniques', 'Initiation to Innovation' and 'Step into Research' for students to improve their career competency. Also, Department focuses on the personality development of the first-year students by providing them with a Skill Development Programme.